Dr. CHEN Siyu (陳思宇)

BMed, MPH, PhD

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Postdoctoral Fellow

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Phone: (852) 2645-3098

Email: siyu.chen@cuhk.edu.hk

• Artificial intelligence (AI) in health promotion and healthcare service delivery

• Digital health interventions for infectious disease prevention and vaccination uptake

• Systematic reviews and meta-analyses for evidence synthesis

• Implementation science and real-world translation of digital innovations

• Health behavior theory–driven intervention design and evaluation

1. Chen S, Yu F, Fang Y, Yau J, Ng N, Zhang Q et al., Chatbot-Delivered Real-Time Support to Improve HIV Self-Testing Rates: A Randomized Clinical Trial. JAMA Netw Open. 2025 Nov24;8(11):e2544821. doi: 10.1001/jamanetworkopen.2025.44821

2. Wang Z, Chen S, Poon J, Han SC, Ye D, Yu FY, Fang Y, Ni Z, Wong MCS, Mo PKH. A Hybrid Chatbot to Promote Pneumococcal Vaccination Among Older Adults: A Randomized Clinical Trial. JAMA Netw Open. 2025 Oct 1;8(10):e2535813. doi: 10.1001/jamanetworkopen.2025.35813

3. Lin Z, Chen S, Su L, Liao Y, Chen H, Hu Z, Chen Z, Fang Y, Liang X, Chen J, Luo B, Wu C, Wang Z. Influences of HPV disease perceptions, vaccine accessibility, and information exposure on social media on HPV vaccination uptake among 11,678 mothers with daughters aged 9-17 years in China: a cross-sectional study. BMC Med. 2024 Aug 13;22(1):328. doi: 10.1186/s12916-024-03538-1 (co-first author)

4. Wang Z, Chen S, Wong NS, Cheung AW, Tam ZP, Chung SL, Chan DP, Mo PKH, Wong EL. Differences in intention to receive clinician-collected and self-collected samples for HPV DNA testing and its determinants between heterosexual males and females in Hong Kong, China: findings of a territory-wide household survey. BMC Med. 2024 Dec 2;22(1):569. doi: 10.1186/s12916-024-03788-z

5. Chen S, Wang S, Cheung D, Fang Y, Sung F, Mo P, Wang Z. Effectiveness of Stage-of-Change (SOC)-tailored Interventions in Increasing Uptake of Any Type of Vaccination: A Systematic Review and Meta-Analysis. Applied Psychology: Health and Well-Being. 2025 2025 May;17(2):e70022. doi: 10.1111/aphw.70022

6. Chen S, Fang Y, Chan PS, Kawuki J, Mo P, Wang Z. Counseling Supporting HIV Self-Testing and Linkage to Care Among Men Who Have Sex With Men: Systematic Review and Meta-Analysis. JMIR Public Health Surveill 2024;10:e45647. doi: 10.2196/45647

7. Chen S, Zhang Q, Chan C, Yu F, Chidgey A, Fang Y, Mo PKH, Wang Z. Evaluating an Innovative HIV Self-Testing Service With Web-Based, Real-Time Counseling Provided by an Artificial Intelligence Chatbot (HIVST-Chatbot) in increasing HIV Self-Testing Use Among Chinese Men Who Have Sex With Men: Protocol for a Noninferiority Randomized Controlled Trial. JMIR Res Protoc 2023;12:e48447. doi: 10.2196/48447

8. Chen S, Yu P, Fang Y, Xin M, Yu F, Ip M, Mo PKH, Wang Z. Patterns and factors of the sexual agreement for extra-dyadic sex among men who have sex with men in Hong Kong, China: a cross-sectional survey. Journal of Sex & Martial Therapy. 2023. https://doi.org/10.1080/0092623X.2023.2279096

9. Lin Z, Chen S (Co-1st), Su L, Cao H, Chen H, Fang Y, Liang X, Chen J, Luo B, Wu C, Wang Z. Associations of mothers' decisional conflicts and satisfaction with governmental health promotion materials with their daughters' HPV vaccination uptake in China: A cross-sectional survey. Vaccine X. 2024 Jul 20;19:100529. doi: 10.1016/j.jvacx.2024.100529

10. Lin Z, Chen S (Co-1st), Su L, Chen H, Fang Y, Liang X, Chan KF, Chen J, Luo B, Wu C, Wang Z. Exploring mother daughter communication and social media influence on HPV vaccine refusal for daughters aged 9-17 years in a cross-sectional survey of 11,728 mothers in China. Hum Vaccin Immunother. 2024 Dec 31;20(1):2333111. doi:10.1080/21645515.2024.2333111